My main instrument is guitar (electric, acoustic, 6/12, etc). I took lessons for three years and then went out on my own. I've been playing, oh, 20+ years now. However, I probably sound like I've been playing for 20 minutes
I played bass in bands in high school and college. I played drums on my own recordings (had a MP3 site up 10 years ago) but my skills have gone to s***. I dabble with the keyboard as well. I first started with the saxophone but probably couldn't do much with one nowadays. I have a harmonica around here somewhere, too.
I recently started taking voice lessons to improve in this area as I've never had confidence in my voice. That will change...hopefully....